Medlešice is a village in Chrudim District, in the Pardubice Region, Czechia. Medlešice lies at 252 m above sea level. The nearest city is Chrudim, 3.6 km to the southeast. Among the landmarks around are Pardubice Castle (6.9 km), Slatiňany Castle (7.3 km) and Kunětická hora Castle (11.6 km). Among the natural features are Topol černý u starého ramene v Polabinách (6.9 km).