Mešno is a village in Rokycany District, in the Plzeň Region, Czechia. Mešno lies at 492 m above sea level. It has 83 inhabitants (2024). The nearest city is Plzeň, 20 km to the west. Among the landmarks around are Cathedral of St. Bartholomew (20 km), Great Synagogue (21 km) and Radyně Castle (11.7 km). Among the natural features are Žďár (9.6 km) and Radyně (11.6 km).