Pyšel is a village in Třebíč District, in the Vysočina Region, Czechia. Pyšel lies at 468 m above sea level. It has 475 inhabitants (2024). The nearest city is Třebíč, 14.4 km to the west. Among the landmarks around are St. Procopius Basilica in Třebíč (14.5 km), Pilgrimage Church of Saint John of Nepomuk (38 km) and Pernštejn Castle (29 km). Among the natural features are Strážná hora (14.7 km) and Ptáčovský kopeček (9.9 km).