Øster Lyby is a settlement in Skive Municipality, in the region of Central Denmark, Denmark. Øster Lyby lies at 24 m above sea level. The nearest city is Skive, 7.2 km to the south. Among the landmarks around are Viborg Cathedral (30 km), Sallingsund Bridge (18.0 km) and Spøttrup Castle (16.4 km).