Megalo Peristeri is a village in Metsovo Municipality, in the regional unit of Ioannina, in the region of Epirus, Greece. Megalo Peristeri lies at 834 m above sea level, at the foot of the Athamanika mountains. It has 181 inhabitants (2021). The nearest city is Ioannina, 19.0 km to the west. Among the landmarks around are Dodona (31 km), Ioannina Castle (18.2 km) and Averoff Gallery (11.6 km). Among the natural features are Katara Pass (16.4 km).

Also written Μεγάλο Περιστέρι.