Pypliškė is a village in Šakiai District Municipality, in Marijampolė County, Lithuania. Pypliškė lies at 67 m above sea level. It has 10 inhabitants. The nearest city is Kaunas, 37 km to the east. Among the landmarks around are Ninth Fort (34 km), M. K. Čiurlionis National Art Museum (38 km) and Church of the Discovery of the Holy Cross, Ilguva (5.2 km). Among the natural features are Ilguva oak (5.1 km).