Palsupė is a village in Biržai District Municipality, in Panevėžys County, Lithuania. Palsupė lies at 66 m above sea level. The nearest city is Panevėžys, 78 km to the southwest. Among the landmarks around are Church of the Assumption of Mary in Skaistkalne (12.3 km), Biržai Castle (21 km) and Lutheran church in Ērberģe (12.0 km).