Simaniai is a village in Biržai District Municipality, in Panevėžys County, Lithuania. Simaniai lies at 72 m above sea level. The nearest city is Panevėžys, 68 km to the southwest. Among the landmarks around are Lutheran church in Nereta (14.5 km), Biržai Castle (20 km) and Church of the Assumption of Mary in Skaistkalne (34 km).