Puplesiai is a village in Joniškis District Municipality, in Šiauliai County, Lithuania. Puplesiai lies at 87 m above sea level. The nearest city is Šiauliai, 31 km to the southwest. Among the landmarks around are Rundāle Palace (39 km), Hill of Crosses (20 km) and Red Synagogue of Joniškis (12.9 km). Among the natural features are Pamūšis thick oak (5.0 km).