Simiškė is a village in Ignalina District Municipality, in Utena County, Lithuania. Simiškė lies at 143 m above sea level. The nearest city is Utena, 63 km to the west. Among the landmarks around are Church of St. John the Baptist, Mielagėnai (3.6 km), Church of the Holy Trinity, Tverečius (10.8 km) and Old Believers Church in Jurgeliškė (7.6 km).