Dereköy is a neighborhood in Karacasu District, in Aydın Province, Türkiye. Dereköy lies at 377 m above sea level, in the Karınçalı Dağı mountains. It has 229 inhabitants. The nearest city is Nazilli, 29 km to the northwest. Among the landmarks around are Aphrodisias (13.1 km), Hierapolis (51 km) and Laodicea on the Lycus (49 km).